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What are DMXEs?

Kaufen Sie DMXE, DMXE  ist eine dissoziative Substanz aus der Klasse der Arylcyclohexylamine, die bei Verabreichung dissoziative, anästhetische, stimulierende und halluzinogene Wirkungen hervorruft.

It was believed to have been first synthesized in 2020 by a laboratory in the Netherlands.

Über DMXE ist aufgrund seiner relativen Neuheit wenig bekannt, daher werden wir Informationen über die chemische Klasse bereitstellen, zu der es gehört – Arylcyclohexylamine.

We also have an ultimate guide to DMXE that is worth reading.

Chemical properties

DMXE is a dissociative arylcyclohexylamine. An arylcyclohexylamine consists of a cyclohexylamine unit with an attached aryl moiety. The aryl group is positioned geminal to the amine. In the simplest cases, the aryl moiety is typically a phenyl ring, sometimes with additional substitution. The amine is usually not primary; secondary amines such as methylamino or ethylamino or tertiary cycloalkylamines such as piperidino and pyrrolidino are the most common N-substituents.

Pharmacological effects

Initial reports suggest that DMXE shares many subjective properties with MXE, more so than other chemicals such as MXPr, MXiPr and DCK.

Due to the lack of research on this substance, all discussions about its pharmacology are based solely on its structure and subjective similarities in action to other arylcyclohexylamine dissociatives such as ketamine, PCE, and methoxetamine (3-MeO-2′-oxo-PCE). Although no scientific studies have been conducted to confirm this, structure-activity relationship analysis suggests that 2′-oxo-PCE probably exhibits its observed effects primarily as an NMDA receptor antagonist, although other neurotransmitter systems may also be involved.

NMDA receptors (a subtype of receptors for glutamate, which are the main excitatory neurotransmitters in the nervous system) allow electrical signals to be transmitted between nerve cells in the brain and spine; for the signals to be transmitted, the receptor must be open. NMDA receptor antagonists have been shown to disrupt this signaling by blocking these receptors. This interruption of the flow of information in the nervous system leads to loss of sensation (anesthesia), difficulty moving (motor discoordination), and ultimately to this substance's equivalent of the "K-hole."

Some of the most commonly reported effects include:

Stimulation

Perception of physical lightness

Physical autonomy

Physical euphoria

dissociation

Improved proprioception

possible side effects

Dizziness

dizziness

Loss of engine control

Orgasm suppression

Mania

legality

DMXE is considered illegal in:

Great Britain

This list is not exhaustive. Please inform yourself about the legal status in your country before ordering!