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Etizolam is a thienodiazepine derivative that acts on the benzodiazepine receptor, making it a benzodiazepine. Etizolam suppliers, Etizolam powder buy, Etizolam Powder Suppliers, Etizolam for Sale, Etizolam Powder Wholesale from China.

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Etizolam powder available in our online store helps you treat generalized anxiety disorder with depression, insomnia and panic disorder.

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Etizolam erhöht die GABAerge Übertragung und verstärkt GABA-induzierte Cl-Ströme, indem es als vollständiger Agonist an GABA-A-Rezeptoren wirkt. Es wird angenommen, dass es an die Benzodiazepin-Bindungsstelle bindet, die sich an der Schnittstelle der Alpha-Gamma-Untereinheit befindet. Berichten zufolge binden Benzodiazepine nur an Rezeptoren, die die Untereinheiten Gamma 2 und Alpha 1/2/3/5 enthalten.

The sedative effect of etizolam is mediated by alpha-1 receptors, and the anxiolytic effect is mediated by receptors containing alpha-2 and alpha-3 subunits. With the combination of alpha-1-beta-2-gamma-2S subunit, etizolam has high potency and affinity for the GABA-A receptor.

Etizolam increases GABA transmission by promoting the opening of GABA-induced chloride channels by binding to the regulatory region of the receptor. Etizolam is a special PAFR antagonist. With an IC50 value of 22 nM, it inhibits PAF-induced platelet aggregation by blocking PAF binding to receptors on platelet surfaces.

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Etizolam is a central nervous system depressant with anxiolytic, anticonvulsant, sedative-hypnotic and muscle relaxant properties. As an agonist, it increases inhibitory GABAergic transmission throughout the central nervous system by binding to the benzodiazepine region of the GABA-A receptor. Studies suggest that etizolam appears to be 6 to 10 times more effective than diazepam in mediating its pharmacological effects.

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