O-PCE HCL

Buy O-PCE HCL online

What is O-PCE?

Buy O-PCE HCL2′-Oxo-PCE (also known as eticyclidone and O-PCE) is a lesser-known novel dissociative substance of the arylcyclohexylamine class that produces dissociative, anaesthetic, stimulant and hallucinogenic effects when administered. It is structurally related to arylcyclohexylamines such as MXE, 3-MeO-PCE and deschloroketamine and it is speculated that it exerts its effects through its activity as an NMDA receptor antagonist.

The structural similarities that O-PCE shares with DCK and ketamine, which are thought to have antibacterial properties,[1][2] have raised concerns about whether it also shares these properties. However, whether this is true is currently entirely uncertain due to the lack of scientific research on the subject. It is recommended that users of this substance keep in mind that the possibility of prolonged use may pose a serious threat to health and the immune system if this is the case.

O-PCE is an example of a modern designer drug that has been specifically selected to mimic and/or replace the functional and structural features of its predecessors. It has recently become widely available through online research chemical suppliers[3], where it is marketed and sold as a designer drug replacement for MXE and other recreational dissociatives. Unlike many other research chemical dissociatives, there is almost no scientific literature on O-PCE, particularly with regard to its toxicity, addiction and abuse potential in humans.

Due to its novelty and extremely short history of human use, any information related to the use of this compound should be treated with extreme caution. Users should also avoid frequent re-dosing, as it has been reported that it is relatively easy to overdose due to its potency and stimulant effects. It is highly recommended that harm reduction measures be used if one chooses to consume this substance.

Chemical properties

O-PCE or 2′-oxo-PCE belongs to the chemical class of arylcyclohexylamines. Arylcyclohexylamine drugs are named for their structure, which includes a cyclohexane ring attached to an aromatic ring, as well as an amine group. Deschloroketamine contains a phenyl ring attached to a cyclohexane ring substituted at R1 with an oxo group (cyclohexanone). Attached to the adjacent alpha carbon (R2) of the cyclohexanone ring is an aminoethyl chain -NCH2CH3. Like MXE, 2′-oxo-PCE contains an aminoethyl chain instead of the aminomethyl chain found in DCK and ketamine. 2′-oxo-PCE is homologous to DCK, differing only in the length of its carbon chain.

Pharmacological effects

Due to the lack of research on this substance, all discussions of its pharmacology are based solely on its structure and subjective similarities in action to other arylcyclohexylamine dissociatives such as ketamine, PCE, and methoxetamine (3-MeO-2′-oxo-PCE). Although no scientific studies have been conducted to confirm this, structure-activity relationship analysis suggests that 2′-oxo-PCE probably exhibits its observed effects primarily as an NMDA receptor antagonist, although other neurotransmitter systems may also be involved.[citation needed]

NMDA receptors (a subtype of receptors for glutamate, which are the main excitatory neurotransmitters in the nervous system) allow electrical signals to be transmitted between nerve cells in the brain and spine; for the signals to be transmitted, the receptor must be open. NMDA receptor antagonists have been shown to disrupt this signaling by blocking these receptors. This interruption of the flow of information in the nervous system leads to loss of sensation (anesthesia), difficulty moving (motor discoordination), and ultimately to this substance's equivalent of the "K-hole."

Some of the most commonly reported effects include:

Stimulation

Perception of physical lightness

Physical autonomy

Physical euphoria

Spontaneous physical sensations

Angstunterdrückung

Cognitive euphoria

Compulsive re-dosing

Conceptual thinking

Increased creativity

Seen

Depersonalization

Derealisation

Disinhibition

Ego-Tod

Memory deletion

Immersion enhancement

Increased appreciation for music

Analysis deletion

Self-observation

Time distortion

Thoughts slowing down

Distortions

Hallucinations

Suppression of visual acuity

Double vision

Removal of pattern recognition

Frame rate removal

Perspective distortions

Environmental Cubism

Environmental orphism

Landscape cutting

possible side effects

amnesia

Nausea

dizziness

Increased pulse

Loss of engine control

Orgasm suppression

Mania

legality

O-PCE is classified as illegal in:

Switzerland

Great Britain

This list is not exhaustive. Please inform yourself about the legal status in your country before ordering!

Where should I buy O-PCE?

We sell high quality O-PCE here at Chems man, typically in powder form. However, we often have other forms available. If the form you require is not shown, please contact us to find out if the item is available in another form.

Our O-PCE is intended for research purposes only and is not intended for internal use by humans or animals. To purchase O-PCE, you must be at least 18 years of age and fully comply with the legal requirements of your country's chemical research laws.

The legality of O-PCE

O-PCE is not legally regulated in most countries around the world. However, it is illegal in the United Kingdom. It could also potentially be illegal in countries with strict laws on analogues, such as the United States.

O-PCE ([SM1] C14H19NO, Mr 254g/mol) is usually supplied in the form of a hydrochloride salt of skin-coloured crystals [SM2] or a powder.

Always store in a cool, dry place to maximise shelf life. This product is intended for forensic and research purposes only. It is therefore NOT intended for human consumption or for in vivo testing of any kind on animals or living organisms.